Original Publications

Hastoy, B., P. A. Scotti, A. Milochau, Z. Fezoua-Boubegtiten, J. Rodas, R. Megret, B. Desbat, M. Laguerre, S. Castano, D. Perrais, P. Rorsman, R. Oda and J. Lang (2017). A Central Small Amino Acid in the VAMP2 Transmembrane Domain Regulates the Fusion Pore in Exocytosis. Scientific Reports 7, Article number: 2835. 

F. Boal, M. Laguerre, A. Milochau, J. Lang and P. A. Scotti. A charged prominence in the linker domain of the cysteine-string protein CSPa mediates its regulated interaction with the calcium sensor synaptotagmin 9 during exocytosis. FASEB J., 2011.

Boal, F., S. Le Pevelen, C. Cziepluch, P. Scotti, and J. Lang, Cysteine-string protein isoform beta (Csp▀) is targeted to the trans-Golgi network as a non-palmitoylated CSP in clonal ▀-cells. Biochim. Biophys. Acta - Mol. Cell Res., 2007. 1773: p. 109-119.

Boal, F., H. Zhang, C. Tessier, P. Scotti, and J. Lang, The variable C-terminus of cysteine string proteins modulates exocytosis and protein-protein interactions. Biochemistry, 2004. 43: p. 16212-16223.

Adams, H., P.A. Scotti, H. De Cock, J. Luirink, and J. Tommassen, The presence of a helix breaker in the hydrophobic core of signal sequences of secretory proteins prevents recognition by the signal-recognition particle in Escherichia coli. Eur. J. Biochem., 2002. 269: p. 5564-5571.

 Adams, H., P.A. Scotti, J. Luirink, and J. Tommassen, Defective translocation of a signal sequence mutant in a prlA4 suppressor strain of Escherichia coli. Eur. J. Biochem., 2002. 269: p. 5572-5580.

Urbanus, M.L., P.A. Scotti, L. Froderberg, A. Saaf, J.W. de Gier, J. Brunner, J.C. Samuelson, R.E. Dalbey, B. Oudega, and J. Luirink, Sec-dependent membrane protein insertion: sequential interaction of nascent FtsQ with SecY and YidC. EMBO Rep., 2001. 2: p. 524-529.

Houben, E.N., P.A. Scotti, Q.A. Valent, J. Brunner, J.L. de Gier, B. Oudega, and J. Luirink, Nascent Lep inserts into the Escherichia coli inner membrane in the vicinity of YidC, SecY and SecA. FEBS Lett., 2000. 476: p. 229-233.

Scotti, P.A., M.L. Urbanus, J. Brunner, J.W. de Gier, G. von Heijne, C. van der Does, A.J. Driessen, B. Oudega, and J. Luirink, YidC, the Escherichia coli homologue of mitochondrial Oxa1p, is a component of the Sec translocase. EMBO J., 2000. 19: p. 542-549.

Cristˇbal S, Scotti PA, Luirink J, von Heijne G & de Gier JW. The SRP-targeting pathway does not necessarly deliver proteins to the Sec-translocase in Escherichia coli. J. Biol. Chem. , 1999. 274: p. 20068-20070.

Scotti, P.A., Q.A. Valent, E.H. Manting, M.L. Urbanus, A.J. Driessen, B. Oudega, and J. Luirink, SecA is not required for signal recognition particle-mediated targeting and initial membrane insertion of a nascent inner membrane protein. J. Biol. Chem., 1999. 274: p. 29883-29888

de Gier, J.W., P.A. Scotti, A. Saaf, Q.A. Valent, A. Kuhn, J. Luirink, and G. von Heijne, Differential use of the signal recognition particle translocase targeting pathway for inner membrane protein assembly in Escherichia coli. Proc. Nat'l Acad. Sci. USA, 1998. 95: p. 14646-14651.

Valent, Q.A., P.A. Scotti, S. High, J.W. de Gier, G. von Heijne, G. Lentzen, W. Wintermeyer, B. Oudega, and J. Luirink, The Escherichia coli SRP and SecB targeting pathways converge at the translocon. EMBO J., 1998. 17: p. 2504-2512.

Turk SCHJ, de Roos K, Scotti PA, van Dun K, Weisbeek P & Smeekens SCM. The vacuolar sorting domain of sporamin transport gus, but not levansucrase to the plant vacuole. New Phytologist, 1997. 136: p. 29-38.

Scotti, P.A., M. Praestegaard, R. Chambert, and M.F. Petit-Glatron, The targeting of Bacillus subtilis levansucrase in yeast is correlated to both the hydrophobicity of the signal peptide and the net charge of the N-terminus mature part. Yeast, 1996. 12: p. 953-963.

Scotti, P.A., R. Chambert, and M.F. Petit-Glatron, Kinetics of the unfolding-folding transition of Bacillus subtilis levansucrase precursor. FEBS Lett., 1995. 360: p. 307-309.

Scotti, P.A., R. Chambert, and M.F. Petit-Glatron, Extracellular levansucrase of Bacillus subtilis produced in yeast remains in the cell in its precursor form. Yeast, 1994. 10: p. 29-38.

Reviews and Book Chapters

Valent Q, O'Gorman EN, Scotti PA, Luirink J & High S. Escherichia coli signal recognition particle - a historical perspective. in "Transport of Molecules Across Microbial Biomembranes"; Ed. J. K. Broome-Smith, S. Baumberg, C. J. Stirling, F. B. Ward. Cambridge University Press, Symposia Society for General Microbiology1999. 55: p. 169-185.